English name

Adenosine 3',5'-cyclic monophosphate

English aliases

cAMP;  Adenosine Cyclophosphate; 

3'-5' cyclic adenosine monophosphate; 5'-Cyclic Monophosphate; (4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide

CAS No.

60-92-4

EINECS No.

200-492-9

Molecular formula

C₁₀H₁₂N₅O₆P

Molecular weight

329.21

Structural formula

Physical properties

This product is a white to off-white powder;odourless； saltish；slightly soluble in water, insoluble in ethanol and ether.

Purity（HPLC）

≥99%-103%

Usage

1.This product is the protein kinase activating agent,which is the department of nucleotide derivatives. It is a important physiologically active substance which widespread presence in the human body, generated by the adenylate cyclase catalytic adenosine triphosphate, can regulate a variety of functional activity of cells. As a second messenger hormones, regulating physiological functions and metabolic substances in cells, can alter the function of cell membranes, prompting the sarcoplasmic reticular calcium into the muscle fibers, thereby enhancing myocardial contractility, and can contribute to respiratory chain oxidative enzyme activity, improve myocardial ischemia, alleviate symptoms of coronary heart disease and improve ECG.Furthermore, it plays an important role in sugar and fat metabolism, nucleic acids, protein synthesis regulation.

2.On clinically the product is used for angina, myocardial infarction, myocarditis and cardiogenic shock. And it has a certain role to improve rheumatic heart palpitations, shortness of breath, chest tightness and other symptoms. Can improve the efficacy of acute leukemia combining with chemotherapy, also can be used for acute leukemia induce remission. In addition, it also have a certain effect on chronic bronchitis, various hepatitis and psoriasis.

Packing size

1kg/bag  5kg/bag  10kg/bag

Storage

Keep dry and away from light and stored in ventilated cool library.